HCP CART FACT SHEET

Review Section

CLICK HERE to review the LLS HCP CART fact sheet for the following items.

  • What is a chimeric antigen receptor (CAR)?
    • Manufacturing a targeted T cell
  • How does CAR T-cell Therapy work?
  • Clinical Trial results
    • Cytokine release syndrome (CRS)
    • Neurotoxicity
    • Macrophage activation syndrome (MAS)/hemophagoccytic lymphomahistiocytosis (HLH)
    • B-cell aplasia (“on-target, off-tumor” toxicity)
    • Table 1. Toxicities associated with CD19-directed CAR T-cell therapy
  • Frequently asked questions
  • We’re Here to Help