HCP CART FACT SHEET

CLICK HERE to review the LLS HCP CART fact sheet for the following items.

• What is a chimeric antigen receptor (CAR)?
  • Manufacturing a targeted T cell
• How does CAR T-cell Therapy work?
• Clinical Trial results
  • Cytokine release syndrome (CRS)
  • Neurotoxicity
  • Macrophage activation syndrome (MAS)/hemophagoccytic lymphomahistiocytosis (HLH)
  • B-cell aplasia (“on-target, off-tumor” toxicity)
  • Table 1. Toxicities associated with CD19-directed CAR T-cell therapy
• Frequently asked questions
• We’re Here to Help